7JHM

Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with N-acetyl-lactosamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2	polymer	370	43300.3	2	UniProt (Q9NY97) Pfam (PF01762) In PDB	Homo sapiens (Human)	Beta-1,3-N-acetylglucosaminyltransferase 1,Beta3Gn-T1,3-galactosyltransferase 7,b3Gal-T7,Beta-3-Gx-T7,UDP-Gal:beta-GlcNAc beta-1,UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,Beta3Gn-T2,UDP-galactose:beta-N-acetylglucosamine beta-1
2	C, D	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
3	E, G	beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		383.3	2	In PDB GlyTouCan (G00055MO)
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	A	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
6		water	water		18.0	241	Chemie (HOH)

Sequence modifications

A, B: 45 - 397 (UniProt: Q9NY97)

PDB	External Database	Details
Met 28	-	initiating methionine
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
Glu 37	-	expression tag
Asn 38	-	expression tag
Leu 39	-	expression tag
Tyr 40	-	expression tag
Phe 41	-	expression tag
Gln 42	-	expression tag
Gly 43	-	expression tag
Ser 44	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86600.5
Branched	Number of molecules	4
	Total formula weight	2588.3
Non-Polymers*	Number of molecules	4
	Total formula weight	946.0
All*	Total formula weight	90134.8

*Water molecules are not included.