7JHL

Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with UDP-N-acetylglucosamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2	polymer	370	43300.3	2	UniProt (Q9NY97) Pfam (PF01762) In PDB	Homo sapiens (Human)	Beta-1,3-N-acetylglucosaminyltransferase 1,Beta3Gn-T1,3-galactosyltransferase 7,b3Gal-T7,Beta-3-Gx-T7,UDP-Gal:beta-GlcNAc beta-1,UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,Beta3Gn-T2,UDP-galactose:beta-N-acetylglucosamine beta-1
2	C, D	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
3	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	A, B	URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE	non-polymer		607.4	2	Chemie (UD1)
5	A, B	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
6	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
7	B	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
8		water	water		18.0	276	Chemie (HOH)

Sequence modifications

A, B: 45 - 397 (UniProt: Q9NY97)

PDB	External Database	Details
Met 28	-	initiating methionine
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
Glu 37	-	expression tag
Asn 38	-	expression tag
Leu 39	-	expression tag
Tyr 40	-	expression tag
Phe 41	-	expression tag
Gln 42	-	expression tag
Gly 43	-	expression tag
Ser 44	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86600.5
Branched	Number of molecules	2
	Total formula weight	1821.6
Non-Polymers*	Number of molecules	10
	Total formula weight	1951.1
All*	Total formula weight	90373.3

*Water molecules are not included.