7JGI

NMR structure of the cNTnC-cTnI chimera bound to A7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle chimera	polymer	125	14186.1	1	UniProt (P63316) UniProt (P19429) Pfam (PF13833)	Homo sapiens (Human)	TN-C,Cardiac troponin I
2	B (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
3	C (A)	7-{[(5-chloronaphthalen-1-yl)sulfonyl]amino}heptanoic acid	non-polymer		369.9	1	Chemie (V8Y)

Sequence modifications

A: 1 - 137 (UniProt: P63316)

PDB	External Database	Details
Ser 35	Cys 35	engineered mutation
Ser 84	Cys 84	engineered mutation

A: 138 - 163 (UniProt: P19429)

PDB	External Database	Details
Gly 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14186.1
Non-Polymers*	Number of molecules	2
	Total formula weight	409.9
All*	Total formula weight	14596.1

*Water molecules are not included.