7JFR
Auristatin bound to tubulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 440 | 48966.3 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | |
| 3 | E (E) | Stathmin-4 | polymer | 138 | 16282.5 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Rat) | Stathmin-like protein B3,RB3 |
| 4 | F (F) | Uncharacterized protein | polymer | 378 | 43549.6 | 1 | UniProt (E1BQ43) | Gallus gallus (Chicken) | |
| 5 | G (L) | Auristatin | polymer | 5 | 873.2 | 1 | BIRD (PRD_002435) | synthetic construct | |
| 6 | H, N (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 7 | I, L, M, O, P (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 8 | J (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 9 | K, Q (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 10 | R (F) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 11 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 258637.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2599.6 | |
| All* | Total formula weight | 261237.4 |
