7HVP
X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS 1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | HIV-1 PROTEASE | polymer | 99 | 10764.6 | 2 | UniProt (P03369) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | |
| 2 | C | INHIBITOR ACE-SER-LEU-ASN-PHE-PSI(CH(OH)-CH2N)-PRO-ILE VME (JG-365) | polymer | 7 | 845.0 | 1 | BIRD (PRD_000228) | ||
| 3 | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Aba 67 | Cys 123 | conflict |
| Aba 95 | Cys 151 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22374.3 | |
| All* | Total formula weight | 22374.3 |
