7HVP
X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS 1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR
Experimental procedure
Spacegroup name | P 21 21 21 |
Unit cell lengths | 51.200, 58.800, 62.000 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 10.000 - 2.400 |
R-factor | 0.146 |
RMSD bond length | 0.020 |
RMSD bond angle | 0.060 |
Refinement software | PROFFT |
Data quality characteristics
Overall | |
High resolution limit [Å] | 2.400 * |
Rmerge | 0.089 * |
Number of reflections | 5398 * |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | Vapor diffusion, hanging drop * | 23 * |
Crystallization Reagents in Literatures
ID | crystal ID | solution | reagent name | concentration (unit) | details |
1 | 1 | reservoir | ammonium sulfate | 55-60 (%(v/v)sat) | |
2 | 1 | reservoir | sodium acetate | 0.1 (M) | |
3 | 1 | drop | protein | 5 (mg/ml) | |
4 | 1 | drop | dimethyl sulfoxide | 9 (%(v/v)) |