7H53
Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with NCL-00024387 (A71EV2A-x1255)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease 2A | polymer | 150 | 16493.3 | 2 | UniProt (Q65900) Pfam (PF00947) | Coxsackievirus A16 | P2A,Picornain 2A,Protein 2A |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | Coxsackievirus A16 | ||
| 3 | D, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 4 | G (B) | 4-bromanyl-1-(2-methoxyethyl)pyridin-2-one | non-polymer | 232.1 | 1 | Chemie (V3U) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 390 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 150 (UniProt: Q65900)
| PDB | External Database | Details |
|---|---|---|
| Gln 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Gln 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Gly 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32986.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 519.2 | |
| All* | Total formula weight | 33505.8 |
