7GQS
Crystal Structure of Werner helicase fragment 517-945 in complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | polymer | 439 | 50064.7 | 1 | UniProt (Q14191) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) | Homo sapiens (human) | |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C, D, E (A) | CADMIUM ION | non-polymer | 112.4 | 3 | Chemie (CD) | |||
| 4 | F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | I (A) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
A: 517 - 945 (UniProt: Q14191)
| PDB | External Database | Details |
|---|---|---|
| Met 516 | - | initiating methionine |
| Gly 946 | - | expression tag |
| Gly 947 | - | expression tag |
| Arg 948 | - | expression tag |
| Leu 949 | - | expression tag |
| Glu 950 | - | expression tag |
| Val 951 | - | expression tag |
| Leu 952 | - | expression tag |
| Phe 953 | - | expression tag |
| Gln 954 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50064.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 924.0 | |
| All* | Total formula weight | 50988.8 |
