7G00

Crystal Structure of human FABP1 in complex with 2-[[3-(5-tert-butyl-1,2,4-oxadiazol-3-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Fatty acid-binding protein, liver	polymer	130	14508.6	16	UniProt (P07148) Pfam (PF14651)	Homo sapiens (human)	Fatty acid-binding protein 1,Liver-type fatty acid-binding protein,L-FABP
2	BA, CA, EA, GA, IA... (F, G, H, I, J...)	2-{[(3P)-3-(5-tert-butyl-1,2,4-oxadiazol-3-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl}cyclopent-1-ene-1-carboxylic acid	non-polymer		415.5	16	Chemie (WII)
3	AA, DA, FA, HA, JA... (F, G, H, I, J...)	THIOCYANATE ION	non-polymer		58.1	16	Chemie (SCN)
4	AB, BB, CB, DB, EB... (E, F, G, H, I...)	water	water		18.0	261	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 1 - 127 (UniProt: P07148)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	232138.3
Non-Polymers*	Number of molecules	32
	Total formula weight	7577.4
All*	Total formula weight	239715.7

*Water molecules are not included.