7FY8
Crystal Structure of human FABP1 in complex with 2-[[4-cyclopropyl-5-methyl-3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Fatty acid-binding protein, liver | polymer | 130 | 14508.6 | 8 | UniProt (P07148) Pfam (PF14651) In PDB | Homo sapiens (human) | Fatty acid-binding protein 1,Liver-type fatty acid-binding protein,L-FABP |
| 2 | A, B, C, D, E... | 2-({(3P)-4-cyclopropyl-5-methyl-3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]thiophen-2-yl}carbamoyl)cyclopent-1-ene-1-carboxylic acid | non-polymer | 427.4 | 8 | Chemie (VI9) | |||
| 3 | A, B, C, D, E... | THIOCYANATE ION | non-polymer | 58.1 | 8 | Chemie (SCN) | |||
| 4 | water | water | 18.0 | 427 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 127 (UniProt: P07148)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 116069.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3883.8 | |
| All* | Total formula weight | 119953.0 |
