7FI3

Archaeal oligopeptide permease A (OppA) from Thermococcus kodakaraensis in complex with an endogenous pentapeptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	ABC-type dipeptide/oligopeptide transport system	polymer	732	84480.2	4	UniProt (Q5JJ92) Pfam (PF00496)	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
2	E, F, G, H (E, F, G, H)	endogenous pentapeptide	polymer	5	443.5	4		synthetic construct
3	I, J, N, O, R... (A, B, C, D)	SODIUM ION	non-polymer		23.0	8	Chemie (NA)
4	K, P (A, B)	HEXAETHYLENE GLYCOL	non-polymer		282.3	2	Chemie (P6G)
5	L, M, Q, T, U... (A, B, C, D)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
6	AA, BA, CA, Z (B, C, D, A)	water	water		18.0	1304	Chemie (HOH)

Sequence modifications

A, B, C, D: 30 - 753 (UniProt: Q5JJ92)

PDB	External Database	Details
Mse 302	Ile 302	engineered mutation
Mse 446	Leu 446	engineered mutation
Mse 557	Leu 557	engineered mutation
Mse 636	Leu 636	engineered mutation
Val 754	-	expression tag
Glu 755	-	expression tag
His 756	-	expression tag
His 757	-	expression tag
His 758	-	expression tag
His 759	-	expression tag
His 760	-	expression tag
His 761	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	339694.9
Non-Polymers*	Number of molecules	17
	Total formula weight	1393.2
All*	Total formula weight	341088.2

*Water molecules are not included.