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7FH0

Crystallographic structure of two neutralizing nanobodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Spike protein S1,Spike protein S1polymer43849299.41UniProt (P0DTC2)
Pfam (PF09408)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
2B, C
(B, C)
nanobodies aRBD-2-7polymer26128131.82Vicugna pacos
3D
(D)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
4E
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
5F, G, H
(A, B)
DI(HYDROXYETHYL)ETHERnon-polymer106.13Chemie (PEG)
6I, J
(B, C)
GLYCEROLnon-polymer92.12Chemie (GOL)
7K, L, M
(A, B, C)
waterwater18.056Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight105563.1
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules6
Total formula weight723.8
All*Total formula weight106711.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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