7FDC

CryoEM Structures of Reconstituted V-ATPase, state3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E	Yeast Vacuolar ATPase A subunit	polymer	617	67796.5	3	Pfam (PF02874) Pfam (PF16886) Pfam (PF00006) UniProt (by SIFTS) (P17255) In PDB	Saccharomyces cerevisiae S288C
2	B, D, F	V-type proton ATPase subunit B	polymer	517	57815.0	3	UniProt (P16140) Pfam (PF02874) Pfam (PF00006) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit B
3	G, I, K	V-type proton ATPase subunit E	polymer	233	26508.4	3	UniProt (P22203) Pfam (PF01991) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit E
4	H, J, L	V-type proton ATPase subunit G	polymer	122	13735.7	3	Pfam (PF03179) UniProt (by SIFTS) (P48836) In PDB	Saccharomyces cerevisiae S288C
5	M	V-type proton ATPase subunit D	polymer	256	29235.0	1	UniProt (P32610) Pfam (PF01813) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit D
6	N	V-type proton ATPase subunit F	polymer	118	13479.2	1	UniProt (P39111) Pfam (PF01990) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit F
7	O	V-type proton ATPase subunit C	polymer	392	44241.4	1	UniProt (P31412) Pfam (PF03223) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit C
8	P	Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT)	polymer	469	53886.0	1	UniProt (P41807) UniProt (Q9UI12) Pfam (PF03224) Pfam (PF11698) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit H
9	Q	Yeast Vacuolar ATPase a subunit	polymer	840	95625.5	1	UniProt (P32563) Pfam (PF01496) In PDB	Saccharomyces cerevisiae S288C	V-ATPase a 1 subunit
10	S	V-type proton ATPase subunit d	polymer	345	39822.5	1	UniProt (P32366) Pfam (PF01992) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit d
11	T	V-type proton ATPase subunit c''	polymer	213	22610.6	1	UniProt (P23968) Pfam (PF00137) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit c''
12	U	V-type proton ATPase subunit c'	polymer	164	17046.4	1	UniProt (P32842) Pfam (PF00137) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit c'
13	V, W, X, Y, Z...	V-type proton ATPase subunit c	polymer	160	16357.5	8	UniProt (P25515) Pfam (PF00137) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit c
14	d	V-type proton ATPase subunit e	polymer	73	8387.1	1	UniProt (Q3E7B6) Pfam (PF05493) In PDB	Saccharomyces cerevisiae S288C	V-ATPase subunit e
15	e	V0 assembly protein 1	polymer	265	29694.9	1	UniProt (P53262) Pfam (PF20520) In PDB	Saccharomyces cerevisiae S288C
16	f	Yeast Vacuolar ATPase f subunit	polymer	85	9369.9	1	UniProt (P0C5R9) In PDB	Saccharomyces cerevisiae S288C

Sequence modifications

P: 1 - 359 (UniProt: P41807)
P: 360 - 469 (UniProt: Q9UI12)

Contents of the asymmetric unit

Polymers	Number of chains	31
	Total formula weight	991825.2
All*	Total formula weight	991825.2

*Water molecules are not included.