7FAR
Crystal structure of PDE5A in complex with inhibitor L12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cGMP-specific 3',5'-cyclic phosphodiesterase | polymer | 349 | 40266.2 | 1 | UniProt (O76074) Pfam (PF00233) In PDB | Homo sapiens (Human) | cGMP-binding cGMP-specific phosphodiesterase,CGB-PDE |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | 5-[bis(fluoranyl)methoxy]-2-[(4-chlorophenyl)methyl]-10-(3-methoxypropyl)-3,10-diazatricyclo[6.4.1.0^{4,13}]trideca-1,4(13),5,7-tetraen-9-one | non-polymer | 448.9 | 1 | Chemie (2VI) | |||
| 5 | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40266.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 538.6 | |
| All* | Total formula weight | 40804.8 |
