7FAK
Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with L96 and L-pro
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prolyl-tRNA synthetase (ProRS) | polymer | 500 | 57937.3 | 1 | UniProt (A0A7J6JUK2) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Toxoplasma gondii | |
| 2 | B (A) | 4-[(3S)-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(5-methoxypyridin-3-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide | non-polymer | 499.5 | 1 | Chemie (1UI) | |||
| 3 | C (A) | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
| 4 | D (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | E, F, G, H, I... (A) | FORMIC ACID | non-polymer | 46.0 | 12 | Chemie (FMT) | |||
| 6 | Q (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | R (A) | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A: 334 - 830 (UniProt: A0A7J6JUK2)
| PDB | External Database | Details |
|---|---|---|
| Gly 331 | - | expression tag |
| Ala 332 | - | expression tag |
| Met 333 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57937.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1421.2 | |
| All* | Total formula weight | 59358.5 |
