7F8H
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A, C | Eyes absent homolog 2 | polymer | 294 | 33026.3 | 3 | UniProt (O00167) Pfam (PF00702) In PDB | Homo sapiens (Human) | |
2 | B, A, C | 3-fluoranyl-~{N}-[(~{E})-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide | non-polymer | 341.4 | 3 | Chemie (1SI) |
Sequence modifications
B, A, C: 253 - 538 (UniProt: O00167)
PDB | External Database | Details |
---|---|---|
Gly 245 | - | expression tag |
Pro 246 | - | expression tag |
Leu 247 | - | expression tag |
Gly 248 | - | expression tag |
Ser 249 | - | expression tag |
Pro 250 | - | expression tag |
Glu 251 | - | expression tag |
Phe 252 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 99079.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1024.1 | |
All* | Total formula weight | 100103.1 |