7F8H
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0007275 | biological_process | multicellular organism development |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0007275 | biological_process | multicellular organism development |
| C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| C | 0007275 | biological_process | multicellular organism development |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:19858093 |
| Chain | Residue | Details |
| B | ASP274 | |
| A | ASP274 | |
| C | ASP274 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton donor => ECO:0000269|PubMed:19858093 |
| Chain | Residue | Details |
| B | ASP276 | |
| A | ASP276 | |
| C | ASP276 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19351884 |
| Chain | Residue | Details |
| B | ASP274 | |
| B | ASP276 | |
| B | ASP502 | |
| A | ASP274 | |
| A | ASP276 | |
| A | ASP502 | |
| C | ASP274 | |
| C | ASP276 | |
| C | ASP502 |
