7F8G
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Eyes absent homolog 2 | polymer | 294 | 33026.3 | 2 | UniProt (O00167) Pfam (PF00702) In PDB | Homo sapiens (Human) | |
2 | B, A | 3-phenoxy-~{N}-[(~{E})-(5-pyrimidin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide | non-polymer | 416.5 | 2 | Chemie (1RI) |
Sequence modifications
B, A: 253 - 538 (UniProt: O00167)
PDB | External Database | Details |
---|---|---|
Gly 245 | - | expression tag |
Pro 246 | - | expression tag |
Leu 247 | - | expression tag |
Gly 248 | - | expression tag |
Ser 249 | - | expression tag |
Pro 250 | - | expression tag |
Glu 251 | - | expression tag |
Phe 252 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 66052.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 832.9 | |
All* | Total formula weight | 66885.6 |