7F8G

Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0007275	biological_process	multicellular organism development
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0007275	biological_process	multicellular organism development

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:19858093

Chain	Residue	Details
A	ASP274
B	ASP274

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000269|PubMed:19858093

Chain	Residue	Details
A	ASP276
B	ASP276

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:19351884

Chain	Residue	Details
A	ASP276
A	ASP502
B	ASP502
A	ASP274
B	ASP274
B	ASP276

---