7F7I

Stapled Peptide Inhibitor in complex with PSD95 GK domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Disks large homolog 4	polymer	205	23611.6	6	UniProt (P31016) Pfam (PF00625)	Rattus norvegicus (Norway rat)
2	G, H, I, J, K... (G, H, I, J, K...)	ACE-ARG-ILE-ARG-ARG-ASP-GLU-TYR-LEU-LYZ-ALA-ILE-GLN-NH2	polymer	14	1603.9	6		synthetic construct
3	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	380	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 531 - 713 (UniProt: P31016)

PDB	External Database	Details
Met 509	-	initiating methionine
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag
Ser 516	-	expression tag
Ser 517	-	expression tag
Gly 518	-	expression tag
Leu 519	-	expression tag
Glu 520	-	expression tag
Val 521	-	expression tag
Leu 522	-	expression tag
Phe 523	-	expression tag
Gln 524	-	expression tag
Gly 525	-	expression tag
Pro 526	-	expression tag
Gly 527	-	expression tag
Ser 528	-	expression tag
Glu 529	-	expression tag
Phe 530	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	151292.7
All*	Total formula weight	151292.7

*Water molecules are not included.