7F79

Crystal structure of glutamate dehydrogenase 3 from Candida albicans in complex with alpha-ketoglutarate and NADPH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Glutamate dehydrogenase	polymer	484	52872.5	6	UniProt (A0A1D8PMH8) Pfam (PF02812) Pfam (PF00208)	Candida albicans SC5314 (Yeast)
2	G, J, M, O, S... (A, B, C, D, E...)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	6	Chemie (NDP)
3	H, K, N, P, T... (A, B, C, D, E...)	2-OXOGLUTARIC ACID	non-polymer		146.1	6	Chemie (AKG)
4	I, L, Q, R, U (A, B, D, E)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
5	AA, BA, CA, X, Y... (D, E, F, A, B...)	water	water		18.0	326	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 456 (UniProt: A0A1D8PMH8)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Leu 457	-	expression tag
Glu 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	317235.0
Non-Polymers*	Number of molecules	17
	Total formula weight	5809.6
All*	Total formula weight	323044.6

*Water molecules are not included.