7F4Z
X-ray crystal structure of Y149A mutated Hsp72-NBD in complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock 70 kDa protein 1B | polymer | 386 | 42673.2 | 1 | UniProt (P0DMV9) Pfam (PF00012) | Homo sapiens (Human) | Heat shock 70 kDa protein 2,HSP70-2,HSP70.2 |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 6 | F (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | G (A) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A: 3 - 380 (UniProt: P0DMV9)
| PDB | External Database | Details |
|---|---|---|
| Ala 149 | Tyr 149 | engineered mutation |
| Leu 381 | - | expression tag |
| Glu 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42673.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 621.0 | |
| All* | Total formula weight | 43294.2 |
