7F0S

A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically 1dynamic RNA-dependent RNA polymerase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-directed RNA polymerase nsP4	polymer	502	54224.8	1	UniProt (P13888) Pfam (PF00978)	Ross river virus (strain T48) (RRV)	Non-structural protein 4,nsP4
2	B (A)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A: 110 - 134 (UniProt: P13888)
A: 135 - 184 (PDB: 7F0S)
A: 185 - 611 (UniProt: P13888)

PDB	External Database	Details
Ala 192	Gln 730	engineered mutation
Ala 196	Gln 734	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54224.8
All*	Total formula weight	54224.8

*Water molecules are not included.