7F0I
phosphodiesterase-9A in complex with inhibitor 4b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | polymer | 533 | 61789.1 | 2 | UniProt (O76083-2) Pfam (PF00233) UniProt (by SIFTS) (O76083) | Homo sapiens (Human) | |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, H (A, B) | 1-cyclopentyl-6-[[(2R)-1-(6-fluoranyl-2-azaspiro[3.3]heptan-2-yl)-1-oxidanylidene-propan-2-yl]amino]-5H-pyrazolo[3,4-d]pyrimidin-4-one | non-polymer | 388.4 | 2 | Chemie (06A) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 123578.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 956.3 | |
| All* | Total formula weight | 124534.5 |
