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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7EWP

Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:1:1 ratio

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)		Probable G-protein coupled receptor 158polymer1138127547.12UniProt (Q5T848)
Pfam (PF22572)
Pfam (PF00003)		Homo sapiens (Human)
2C
(C)		Regulator of G-protein signaling 7polymer53061570.11UniProt (P49802)
Pfam (PF00610)
Pfam (PF18148)
Pfam (PF00631)
Pfam (PF00615)		Homo sapiens (Human)RGS7
3D
(D)		Guanine nucleotide-binding protein subunit beta-5polymer39543619.31UniProt (O14775)
Pfam (PF00400)		Homo sapiens (Human)Gbeta5,Transducin beta chain 5
Sequence modifications
A, B: 1 - 863 (UniProt: Q5T848)
PDBExternal DatabaseDetails
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C: 1 - 495 (UniProt: P49802)
PDBExternal DatabaseDetails
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Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight360283.6
All*Total formula weight360283.6
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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