7EWH
Crystal structure of human PHGDH in complex with Homoharringtonine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | D-3-phosphoglycerate dehydrogenase | polymer | 302 | 32454.4 | 2 | UniProt (O43175) Pfam (PF00389) Pfam (PF02826) | Homo sapiens (Human) | 3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase |
| 2 | C, D (A, B) | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine | non-polymer | 545.6 | 2 | Chemie (HMT) PubChem (3628) PubChem (285033) PubChem (5458297) PubChem (6604865) PubChem (10951700) PubChem (14368099) PubChem (14368100) PubChem (45356872) PubChem (56841046) PubChem (60128444) PubChem (71211769) PubChem (72332) PubChem (53298607) PubChem (93956057) PubChem (138107280) PubChem (58786313) PubChem (60128438) PubChem (68337922) PubChem (70826802) PubChem (70826803) PubChem (71296925) PubChem (90392075) PubChem (92850103) PubChem (92850104) PubChem (93956055) PubChem (93956056) PubChem (93956058) PubChem (118911842) PubChem (140440283) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64908.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1091.2 | |
| All* | Total formula weight | 66000.0 |
