7EWH
Crystal structure of human PHGDH in complex with Homoharringtonine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | D-3-phosphoglycerate dehydrogenase | polymer | 302 | 32454.4 | 2 | UniProt (O43175) Pfam (PF00389) Pfam (PF02826) | Homo sapiens (Human) | 3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase |
| 2 | C, D (A, B) | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine | non-polymer | 545.6 | 2 | Chemie (HMT) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64908.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1091.2 | |
| All* | Total formula weight | 66000.0 |
