7EPM
human LDHC complexed with NAD+ and ethylamino acetic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | L-lactate dehydrogenase C chain | polymer | 341 | 37528.4 | 2 | UniProt (P07864) Pfam (PF00056) Pfam (PF02866) In PDB | Homo sapiens (Human) | LDH-C,Cancer/testis antigen 32,CT32,LDH testis subunit,LDH-X |
2 | A, B | 2-(ethylamino)-2-oxidanylidene-ethanoic acid | non-polymer | 117.1 | 2 | Chemie (J9X) | |||
3 | A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
4 | A, B | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
5 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 333 (UniProt: P07864)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ala 2 | - | expression tag |
Glu 56 | Leu 55 | engineered mutation |
Gln 332 | Ile 331 | engineered mutation |
Leu 334 | - | expression tag |
Glu 335 | - | expression tag |
His 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
His 341 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75056.8 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 2425.6 | |
All* | Total formula weight | 77482.4 |