7EPC

Cryo-EM structure of inactive mGlu7 homodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Isoform 3 of Metabotropic glutamate receptor 7	polymer	857	96277.0	2	UniProt (Q14831-3) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) UniProt (by SIFTS) (Q14831) In PDB	Homo sapiens (Human)	mGluR7

Sequence modifications

A, B: 35 - 859 (UniProt: Q14831-3)

PDB	External Database	Details
Gly 32	-	expression tag
Ala 33	-	expression tag
Pro 34	-	expression tag
Tyr 678	Asn 678	engineered mutation
Ile 722	Gly 722	engineered mutation
Phe 775	Ile 775	engineered mutation
Tyr 789	Pro 789	engineered mutation
Glu 860	-	expression tag
Phe 861	-	expression tag
Leu 862	-	expression tag
Glu 863	-	expression tag
Val 864	-	expression tag
Leu 865	-	expression tag
Phe 866	-	expression tag
Gln 867	-	expression tag
Gly 868	-	expression tag
Pro 869	-	expression tag
Gly 870	-	expression tag
Ser 871	-	expression tag
Gly 872	-	expression tag
Ser 873	-	expression tag
Trp 874	-	expression tag
Ser 875	-	expression tag
His 876	-	expression tag
Pro 877	-	expression tag
Gln 878	-	expression tag
Phe 879	-	expression tag
Glu 880	-	expression tag
Lys 881	-	expression tag
Asp 882	-	expression tag
Tyr 883	-	expression tag
Lys 884	-	expression tag
Asp 885	-	expression tag
Asp 886	-	expression tag
Asp 887	-	expression tag
Asp 888	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	192554.0
All*	Total formula weight	192554.0

*Water molecules are not included.