7EPA

Cryo-EM structure of inactive mGlu2 homodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Metabotropic glutamate receptor 2	polymer	822	91111.3	2	UniProt (Q14416) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003)	Homo sapiens (Human)	mGluR2

Sequence modifications

A, B: 19 - 825 (UniProt: Q14416)

PDB	External Database	Details
Asp 12	-	expression tag
Tyr 13	-	expression tag
Lys 14	-	expression tag
Asp 15	-	expression tag
Asp 16	-	expression tag
Asp 17	-	expression tag
Asp 18	-	expression tag
Tyr 655	Asn 655	engineered mutation
Tyr 815	His 815	engineered mutation
Glu 826	-	expression tag
Phe 827	-	expression tag
Leu 828	-	expression tag
Glu 829	-	expression tag
Val 830	-	expression tag
Leu 831	-	expression tag
Phe 832	-	expression tag
Gln 833	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	182222.6
All*	Total formula weight	182222.6

*Water molecules are not included.