7EMN

The atomic structure of SHP2 E76A mutant

Replaces:  6IHZ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tyrosine-protein phosphatase non-receptor type 11	polymer	534	61390.3	2	UniProt (Q06124) Pfam (PF00017) Pfam (PF00102) In PDB	Homo sapiens (Human)	Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3
2		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A, B: 1 - 534 (UniProt: Q06124)

PDB	External Database	Details
Ala 76	Glu 76	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122780.5
All*	Total formula weight	122780.5

*Water molecules are not included.