7EMF
Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mediator of RNA polymerase II transcription subunit 1 | polymer | 1581 | 168697.3 | 1 | UniProt (Q15648) Pfam (PF10744) | Homo sapiens (Human) | |
| 2 | B (B) | Unknown Chain (poly A) | polymer | 20 | 1439.6 | 1 | Homo sapiens (Human) | ||
| 3 | C (D) | Mediator of RNA polymerase II transcription subunit 4 | polymer | 270 | 29781.4 | 1 | UniProt (Q9NPJ6) Pfam (PF10018) | Homo sapiens (Human) | |
| 4 | D (F) | Mediator of RNA polymerase II transcription subunit 6 | polymer | 246 | 28464.6 | 1 | UniProt (O75586) Pfam (PF04934) | Homo sapiens (Human) | |
| 5 | E (G) | Mediator of RNA polymerase II transcription subunit 7 | polymer | 233 | 27285.3 | 1 | UniProt (O43513) Pfam (PF05983) | Homo sapiens (Human) | |
| 6 | F (H) | Isoform 2 of Mediator of RNA polymerase II transcription subunit 8 | polymer | 268 | 29112.9 | 1 | UniProt (Q96G25) Pfam (PF10232) | Homo sapiens (Human) | |
| 7 | G (I) | Mediator of RNA polymerase II transcription subunit 9 | polymer | 146 | 16422.8 | 1 | UniProt (Q9NWA0) Pfam (PF07544) | Homo sapiens (Human) | |
| 8 | H (J) | Mediator of RNA polymerase II transcription subunit 10 | polymer | 135 | 15711.0 | 1 | UniProt (Q9BTT4) Pfam (PF09748) | Homo sapiens (Human) | |
| 9 | I (K) | Mediator of RNA polymerase II transcription subunit 11 | polymer | 117 | 13145.8 | 1 | UniProt (Q9P086) Pfam (PF10280) | Homo sapiens (Human) | |
| 10 | J (N) | Mediator of RNA polymerase II transcription subunit 14 | polymer | 1454 | 160787.6 | 1 | UniProt (O60244) Pfam (PF08638) Pfam (PF22981) Pfam (PF22984) Pfam (PF22983) | Homo sapiens (Human) | |
| 11 | K (O) | Mediator of RNA polymerase II transcription subunit 15 | polymer | 788 | 86830.1 | 1 | UniProt (Q96RN5) Pfam (PF09606) Pfam (PF21538) Pfam (PF21539) | Homo sapiens (Human) | |
| 12 | L (P) | Isoform 2 of Mediator of RNA polymerase II transcription subunit 16 | polymer | 841 | 93136.0 | 1 | UniProt (Q9Y2X0) Pfam (PF00400) Pfam (PF11635) Pfam (PF20718) Pfam (PF20719) | Homo sapiens (Human) | |
| 13 | M (Q) | Mediator of RNA polymerase II transcription subunit 17 | polymer | 651 | 72984.0 | 1 | UniProt (Q9NVC6) Pfam (PF10156) | Homo sapiens (Human) | |
| 14 | N (R) | Mediator of RNA polymerase II transcription subunit 18 | polymer | 208 | 23693.7 | 1 | UniProt (Q9BUE0) Pfam (PF09637) | Homo sapiens (Human) | |
| 15 | O (S) | Mediator of RNA polymerase II transcription subunit 19 | polymer | 244 | 26321.1 | 1 | UniProt (A0JLT2) Pfam (PF10278) | Homo sapiens (Human) | |
| 16 | P (T) | Mediator of RNA polymerase II transcription subunit 20 | polymer | 212 | 23243.8 | 1 | UniProt (Q9H944) Pfam (PF08612) | Homo sapiens (Human) | |
| 17 | Q (U) | Mediator of RNA polymerase II transcription subunit 21 | polymer | 144 | 15575.2 | 1 | UniProt (Q13503) Pfam (PF11221) | Homo sapiens (Human) | |
| 18 | R (V) | Mediator of RNA polymerase II transcription subunit 22 | polymer | 200 | 22243.7 | 1 | UniProt (Q15528) Pfam (PF06179) | Homo sapiens (Human) | |
| 19 | S (W) | Mediator of RNA polymerase II transcription subunit 23 | polymer | 1368 | 156652.2 | 1 | UniProt (Q9ULK4) Pfam (PF11573) | Homo sapiens (Human) | |
| 20 | T (X) | Mediator of RNA polymerase II transcription subunit 24 | polymer | 989 | 110430.2 | 1 | UniProt (O75448) Pfam (PF11277) | Homo sapiens (Human) | |
| 21 | U (Y) | Mediator of RNA polymerase II transcription subunit 25 | polymer | 747 | 78230.3 | 1 | UniProt (Q71SY5) Pfam (PF11265) Pfam (PF11235) Pfam (PF11232) | Homo sapiens (Human) | |
| 22 | V (Z) | Mediator of RNA polymerase II transcription subunit 26 | polymer | 600 | 65544.4 | 1 | UniProt (O95402) Pfam (PF08711) Pfam (PF15694) Pfam (PF15693) | Homo sapiens (Human) | |
| 23 | W (0) | Mediator of RNA polymerase II transcription subunit 27 | polymer | 311 | 35478.7 | 1 | UniProt (Q6P2C8) Pfam (PF11571) | Homo sapiens (Human) | |
| 24 | X (1) | Mediator of RNA polymerase II transcription subunit 28 | polymer | 178 | 19540.1 | 1 | UniProt (Q9H204) Pfam (PF11594) | Homo sapiens (Human) | |
| 25 | Y (2) | Mediator of RNA polymerase II transcription subunit 29 | polymer | 200 | 21089.8 | 1 | UniProt (Q9NX70) Pfam (PF11568) | Homo sapiens (Human) | |
| 26 | Z (3) | Mediator of RNA polymerase II transcription subunit 30 | polymer | 178 | 20301.2 | 1 | UniProt (Q96HR3) Pfam (PF11315) | Homo sapiens (Human) | |
| 27 | AA (4) | Mediator of RNA polymerase II transcription subunit 31 | polymer | 131 | 15826.1 | 1 | UniProt (Q9Y3C7) Pfam (PF05669) | Homo sapiens (Human) | |
| 28 | BA, CA (P, 0) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 27 |
| Total formula weight | 1377969.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 1378100.0 |
