7EM7
Crystal structure of the PI5P4Kbeta N203D-XTP complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | polymer | 393 | 44929.9 | 2 | UniProt (P78356) Pfam (PF01504) In PDB | Homo sapiens (Human) | 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta,Diphosphoinositide kinase 2-beta,Phosphatidylinositol 5-phosphate 4-kinase type II beta,PI(5)P 4-kinase type II beta,PIP4KII-beta,PtdIns(5)P-4-kinase isoform 2-beta |
2 | A | [(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate | non-polymer | 444.2 | 1 | Chemie (CZC) | |||
3 | A | [[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 524.2 | 1 | Chemie (CZF) |
Sequence modifications
A, B: 31 - 416 (UniProt: P78356)
PDB | External Database | Details |
---|---|---|
Gly 24 | - | expression tag |
Pro 25 | - | expression tag |
Asn 26 | - | expression tag |
Cys 27 | - | expression tag |
Ala 28 | - | expression tag |
Pro 29 | - | expression tag |
Gly 30 | - | expression tag |
Asp 203 | Asn 203 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 89859.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 968.3 | |
All* | Total formula weight | 90828.1 |