7EM2
Crystal structure of the PI5P4Kbeta-XTP complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | polymer | 393 | 44928.9 | 2 | UniProt (P78356) Pfam (PF01504) | Homo sapiens (Human) | 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta,Diphosphoinositide kinase 2-beta,Phosphatidylinositol 5-phosphate 4-kinase type II beta,PIP4KII-beta,PtdIns(5)P-4-kinase isoform 2-beta |
| 2 | C, E (A, B) | [(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate | non-polymer | 444.2 | 2 | Chemie (CZC) | |||
| 3 | D (A) | [[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 524.2 | 1 | Chemie (CZF) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 416 (UniProt: P78356)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Asn 26 | - | expression tag |
| Cys 27 | - | expression tag |
| Ala 28 | - | expression tag |
| Pro 29 | - | expression tag |
| Gly 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89857.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1412.5 | |
| All* | Total formula weight | 91270.3 |
