7EL4

The crystal structure of p53p peptide fragment in complex with the N-terminal domain of MdmX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cellular tumor antigen p53,Protein Mdm4	polymer	130	14626.5	1	UniProt (P04637) UniProt (O15151) In PDB	Homo sapiens (Human)	Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4
2	A	1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE	non-polymer		264.3	2	Chemie (O4B)
3	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4		water	water		18.0	36	Chemie (HOH)

Sequence modifications

A: 22 - 28 (UniProt: P04637)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
Ser 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Ser 10	-	expression tag
Gln 11	-	expression tag
Asp 12	-	expression tag
Leu 13	-	expression tag
Glu 14	-	expression tag
Asn 15	-	expression tag
Leu 16	-	expression tag
Tyr 17	-	expression tag
Phe 18	-	expression tag
Gln 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Gly 29	-	linker
Ser 30	-	linker
Gly 31	-	linker
Ser 32	-	linker
Ser 33	-	linker
Glu 34	-	linker
Asn 35	-	linker
Ser 36	-	linker
Gly 37	-	linker
Phe 38	-	linker
Ser 39	-	linker
Gly 40	-	linker
Ser 41	-	linker

A: 42 - 130 (UniProt: O15151)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14626.5
Non-Polymers*	Number of molecules	4
	Total formula weight	577.2
All*	Total formula weight	15203.8

*Water molecules are not included.