7EIZ
Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | RNA-directed RNA polymerase | polymer | 929 | 106440.6 | 1 | UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | Pol,RdRp,Non-structural protein 12,nsp12 |
2 | B, D (B, D) | Non-structural protein 8 | polymer | 198 | 21903.0 | 2 | UniProt (P0DTD1) Pfam (PF08717) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | nsp8 |
3 | C (C) | Non-structural protein 7 | polymer | 83 | 9248.8 | 1 | UniProt (P0DTC1) Pfam (PF08716) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | nsp7 |
4 | E (G) | Non-structural protein 9 | polymer | 113 | 12391.2 | 1 | UniProt (P0DTD1) Pfam (PF08710) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | nsp9 |
5 | F (H) | Non-structural protein 10 | polymer | 139 | 14802.9 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | nsp10,Growth factor-like peptide,GFL |
6 | G (I) | primer | polymer | 25 | 8172.9 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
7 | H (J) | template | polymer | 27 | 8522.1 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
8 | I (K) | Proofreading exoribonuclease | polymer | 527 | 59887.5 | 1 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | ExoN,Guanine-N7 methyltransferase,Non-structural protein 14,nsp14 |
9 | J, K (E, F) | Helicase | polymer | 601 | 66930.5 | 2 | UniProt (P0DTD1) Pfam (PF20632) Pfam (PF20633) Pfam (PF20631) Pfam (PF13087) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Hel, Non-structural protein 13, nsp13 |
10 | L, M, N, O, P... (A, H, K, E, F) | ZINC ION | non-polymer | 65.4 | 13 | Chemie (ZN) | |||
11 | S (K) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 11 |
Total formula weight | 397133.1 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 874.6 | |
All* | Total formula weight | 398007.7 |