7EIC
Crystal structure of AF9 YEATS domain in complex with H4K5acK8ac peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Histone H4 | polymer | 12 | 1187.4 | 1 | UniProt (P62805) | Homo sapiens | |
| 2 | B, C (A, B) | Protein AF-9 | polymer | 145 | 16848.4 | 2 | UniProt (P42568) Pfam (PF03366) | Homo sapiens (Human) | ALL1-fused gene from chromosome 9 protein,Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein,YEATS domain-containing protein 3 |
| 3 | D, E, G, H (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | F, I, J (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 5 | K, L, M (C, A, B) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 138 (UniProt: P42568)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34884.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 686.7 | |
| All* | Total formula weight | 35570.8 |
