7EHM
Human MTHFD2 in complex with compound 21 and 15
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial | polymer | 315 | 34183.6 | 2 | UniProt (P13995) Pfam (PF00763) Pfam (PF02882) | Homo sapiens (Human) | |
| 2 | C, E (A, B) | (2S)-2-[[4-[[1-[(3,4-dichlorophenyl)methyl]-3,7-dimethyl-2,6-bis(oxidanylidene)purin-8-yl]amino]phenyl]carbonylamino]pentanedioic acid | non-polymer | 603.4 | 2 | Chemie (J4C) | |||
| 3 | D, F (A, B) | (2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acid | non-polymer | 418.4 | 2 | Chemie (J49) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68367.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2043.5 | |
| All* | Total formula weight | 70410.7 |
