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7EHJ

human MTHFD2 in complex with compound 21, cofactor and phosphate.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialpolymer31534183.62UniProt (P13995)
Pfam (PF00763)
Pfam (PF02882)
In PDB
Homo sapiens (Human)
2A, B(2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acidnon-polymer418.42Chemie (J49)
3A, BNICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.42Chemie (NAD)
4APHOSPHATE IONnon-polymer95.02Chemie (PO4)
5waterwater18.0213Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68367.1
Non-Polymers*Number of molecules6
Total formula weight2353.5
All*Total formula weight70720.6
*Water molecules are not included.

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PDB entries from 2024-09-11

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