7EHJ
human MTHFD2 in complex with compound 21, cofactor and phosphate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial | polymer | 315 | 34183.6 | 2 | UniProt (P13995) Pfam (PF00763) Pfam (PF02882) | Homo sapiens (Human) | |
| 2 | C, G (A, B) | (2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic acid | non-polymer | 418.4 | 2 | Chemie (J49) | |||
| 3 | D, H (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | E, F (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68367.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2353.5 | |
| All* | Total formula weight | 70720.6 |
