7EEB
Structure of the CatSpermasome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Enhanced green fluorescent protein,Cation channel sperm-associated protein 1 | polymer | 955 | 109442.8 | 1 | UniProt (C5MKY7) UniProt (Q91ZR5) Pfam (PF00520) | Human cytomegalovirus (HHV-5 Human herpesvirus 5) | CatSper1 |
| 2 | B (B) | Cation channel sperm-associated protein 2 | polymer | 588 | 68651.1 | 1 | UniProt (A2ARP9) Pfam (PF00520) | Mus musculus (Mouse) | CatSper2 |
| 3 | C (C) | Cation channel sperm-associated protein 3 | polymer | 395 | 45533.1 | 1 | UniProt (Q80W99) Pfam (PF00520) Pfam (PF08016) | Mus musculus (Mouse) | CatSper3 |
| 4 | D (D) | Cation channel sperm-associated protein 4 | polymer | 442 | 51179.3 | 1 | UniProt (Q8BVN3) Pfam (PF00520) Pfam (PF08016) | Mus musculus (Mouse) | CatSper4 |
| 5 | E (E) | Cation channel sperm-associated protein subunit beta | polymer | 1109 | 126250.0 | 1 | UniProt (A2RTF1) Pfam (PF22831) Pfam (PF15149) Pfam (PF21541) Pfam (PF21548) Pfam (PF22830) | Mus musculus (Mouse) | CatSper-beta |
| 6 | F (F) | Cation channel sperm-associated protein subunit gamma 2 | polymer | 1145 | 131550.6 | 1 | UniProt (C6KI89) Pfam (PF22840) Pfam (PF15064) Pfam (PF22851) Pfam (PF22846) | Mus musculus (Mouse) | |
| 7 | G (G) | Cation channel sperm-associated protein subunit delta | polymer | 805 | 91186.5 | 1 | UniProt (E9Q9F6) Pfam (PF15020) Pfam (PF22850) | Mus musculus (Mouse) | CatSper-delta,CatSperdelta,Transmembrane protein 146 |
| 8 | H (H) | Cation channel sperm-associated protein subunit epsilon | polymer | 985 | 113913.5 | 1 | UniProt (P0DP43) Pfam (PF22841) Pfam (PF22843) Pfam (PF22844) Pfam (PF22849) Pfam (PF22850) | Mus musculus (Mouse) | CatSper-epsilon,CatSperepsilon,C1orf101-like protein |
| 9 | I (L) | Kazal-like domain-containing protein | polymer | 706 | 79055.3 | 1 | UniProt (Q3V161) Pfam (PF03137) Pfam (PF07648) UniProt (by SIFTS) (Q8C0X7) | Mus musculus (Mouse) | |
| 10 | J (J) | Transmembrane protein 249 | polymer | 171 | 19918.4 | 1 | UniProt (A0A2R8VHF7) Pfam (PF15158) | Mus musculus (Mouse) | |
| 11 | K (M) | Transmembrane protein 262 | polymer | 116 | 13489.0 | 1 | UniProt (D3Z338) | Mus musculus (Mouse) | |
| 12 | L (N) | Unknown | polymer | 28 | 2401.0 | 1 | Mus musculus (Mouse) | ||
| 13 | M (I) | EF-hand calcium-binding domain-containing protein 9 | polymer | 216 | 26170.5 | 1 | UniProt (Q9DAM2) | Mus musculus (Mouse) | |
| 14 | N (K) | Cation channel sperm-associated protein subunit zeta | polymer | 194 | 22776.6 | 1 | UniProt (Q9CQP8) | Mus musculus (Mouse) | CatSper-zeta,CatSperzeta,Protein expressed in male leptotene and zygotene spermatocytes 622,MLZ-622,Testis-expressed protein 40 |
| 15 | O (O) | beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G01504UZ) | |||
| 16 | AA, DA, P, S, T... (a, d, P, S, T...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 7 | In PDB GlyTouCan (G42666HT) | |||
| 17 | BA, Q, R, U, W (b, Q, R, U, W) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 18 | CA, Y (c, Y) | beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G89225LT) | |||
| 19 | Z (Z) | beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G42553TN) | |||
| 20 | EA, IA (A, D) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 21 | FA, GA, HA (A) | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 3 | Chemie (9Z9) | |||
| 22 | JA, KA, LA, MA, NA... (E, F, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
A: -246 - -8 (UniProt: C5MKY7)
A: 1 - 686 (UniProt: Q91ZR5)
| PDB | External Database | Details |
|---|---|---|
| Asp -268 | - | expression tag |
| Tyr -267 | - | expression tag |
| Lys -266 | - | expression tag |
| Asp -265 | - | expression tag |
| His -264 | - | expression tag |
| Asp -263 | - | expression tag |
| Gly -262 | - | expression tag |
| Asp -261 | - | expression tag |
| Tyr -260 | - | expression tag |
| Lys -259 | - | expression tag |
| Asp -258 | - | expression tag |
| His -257 | - | expression tag |
| Asp -256 | - | expression tag |
| Ile -255 | - | expression tag |
| Asp -254 | - | expression tag |
| Tyr -253 | - | expression tag |
| Lys -252 | - | expression tag |
| Asp -251 | - | expression tag |
| Asp -250 | - | expression tag |
| Asp -249 | - | expression tag |
| Asp -248 | - | expression tag |
| Lys -247 | - | expression tag |
| Glu -7 | - | linker |
| Asn -6 | - | linker |
| Leu -5 | - | linker |
| Tyr -4 | - | linker |
| Phe -3 | - | linker |
| Gln -2 | - | linker |
| Gly -1 | - | linker |
| Ser 0 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 901517.4 | |
| Branched | Number of molecules | 16 |
| Total formula weight | 10195.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3671.3 | |
| All* | Total formula weight | 915384.1 |
