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7EEB

Structure of the CatSpermasome

Functional Information from GO Data
ChainGOidnamespacecontents
A0005216molecular_functionmonoatomic ion channel activity
A0005227molecular_functioncalcium-activated cation channel activity
A0005245molecular_functionvoltage-gated calcium channel activity
A0005262molecular_functioncalcium channel activity
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0006816biological_processcalcium ion transport
A0007283biological_processspermatogenesis
A0007342biological_processfusion of sperm to egg plasma membrane involved in single fertilization
A0008218biological_processbioluminescence
A0016020cellular_componentmembrane
A0030154biological_processcell differentiation
A0030317biological_processflagellated sperm motility
A0031514cellular_componentmotile cilium
A0034702cellular_componentmonoatomic ion channel complex
A0036128cellular_componentCatSper complex
A0051924biological_processregulation of calcium ion transport
A0055085biological_processtransmembrane transport
A0060296biological_processregulation of cilium beat frequency involved in ciliary motility
A0070588biological_processcalcium ion transmembrane transport
A0097228cellular_componentsperm principal piece
B0005216molecular_functionmonoatomic ion channel activity
B0005227molecular_functioncalcium-activated cation channel activity
B0005245molecular_functionvoltage-gated calcium channel activity
B0005262molecular_functioncalcium channel activity
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0006816biological_processcalcium ion transport
B0007283biological_processspermatogenesis
B0009566biological_processfertilization
B0016020cellular_componentmembrane
B0030154biological_processcell differentiation
B0030317biological_processflagellated sperm motility
B0031514cellular_componentmotile cilium
B0034702cellular_componentmonoatomic ion channel complex
B0036126cellular_componentsperm flagellum
B0036128cellular_componentCatSper complex
B0048240biological_processsperm capacitation
B0055085biological_processtransmembrane transport
B0070588biological_processcalcium ion transmembrane transport
C0001669cellular_componentacrosomal vesicle
C0005216molecular_functionmonoatomic ion channel activity
C0005245molecular_functionvoltage-gated calcium channel activity
C0005262molecular_functioncalcium channel activity
C0005515molecular_functionprotein binding
C0005783cellular_componentendoplasmic reticulum
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0006814biological_processsodium ion transport
C0007283biological_processspermatogenesis
C0016020cellular_componentmembrane
C0030154biological_processcell differentiation
C0030317biological_processflagellated sperm motility
C0031514cellular_componentmotile cilium
C0034702cellular_componentmonoatomic ion channel complex
C0036128cellular_componentCatSper complex
C0048240biological_processsperm capacitation
C0051649biological_processestablishment of localization in cell
C0055085biological_processtransmembrane transport
C0070588biological_processcalcium ion transmembrane transport
D0001669cellular_componentacrosomal vesicle
D0005216molecular_functionmonoatomic ion channel activity
D0005227molecular_functioncalcium-activated cation channel activity
D0005245molecular_functionvoltage-gated calcium channel activity
D0005262molecular_functioncalcium channel activity
D0005515molecular_functionprotein binding
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0006814biological_processsodium ion transport
D0007283biological_processspermatogenesis
D0016020cellular_componentmembrane
D0030154biological_processcell differentiation
D0030317biological_processflagellated sperm motility
D0031514cellular_componentmotile cilium
D0034702cellular_componentmonoatomic ion channel complex
D0036128cellular_componentCatSper complex
D0048240biological_processsperm capacitation
D0051649biological_processestablishment of localization in cell
D0055085biological_processtransmembrane transport
D0070588biological_processcalcium ion transmembrane transport
D0097228cellular_componentsperm principal piece
E0005515molecular_functionprotein binding
E0005886cellular_componentplasma membrane
E0005929cellular_componentcilium
E0007283biological_processspermatogenesis
E0030154biological_processcell differentiation
E0031514cellular_componentmotile cilium
E0034702cellular_componentmonoatomic ion channel complex
E0036128cellular_componentCatSper complex
E0048240biological_processsperm capacitation
E0097228cellular_componentsperm principal piece
F0036128cellular_componentCatSper complex
F0097228cellular_componentsperm principal piece
G0036128cellular_componentCatSper complex
H0036128cellular_componentCatSper complex
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005516molecular_functioncalmodulin binding
I0005737cellular_componentcytoplasm
I0007283biological_processspermatogenesis
I0030154biological_processcell differentiation
I0030317biological_processflagellated sperm motility
I0031514cellular_componentmotile cilium
I0036128cellular_componentCatSper complex
I0046872molecular_functionmetal ion binding
I0048240biological_processsperm capacitation
I0061891molecular_functioncalcium ion sensor activity
I0097228cellular_componentsperm principal piece
J0003674molecular_functionmolecular_function
J0005886cellular_componentplasma membrane
J0008150biological_processbiological_process
J0031514cellular_componentmotile cilium
J0036128cellular_componentCatSper complex
J0097228cellular_componentsperm principal piece
K0003674molecular_functionmolecular_function
K0005515molecular_functionprotein binding
K0005737cellular_componentcytoplasm
K0005886cellular_componentplasma membrane
K0007140biological_processmale meiotic nuclear division
K0007283biological_processspermatogenesis
K0030154biological_processcell differentiation
K0030317biological_processflagellated sperm motility
K0031514cellular_componentmotile cilium
K0036128cellular_componentCatSper complex
K0048240biological_processsperm capacitation
K0097228cellular_componentsperm principal piece
L0005886cellular_componentplasma membrane
L0008514molecular_functionorganic anion transmembrane transporter activity
L0015347molecular_functionsodium-independent organic anion transmembrane transporter activity
L0015711biological_processorganic anion transport
L0016020cellular_componentmembrane
L0016323cellular_componentbasolateral plasma membrane
L0031514cellular_componentmotile cilium
L0036128cellular_componentCatSper complex
L0043252biological_processsodium-independent organic anion transport
L0055085biological_processtransmembrane transport
M0003674molecular_functionmolecular_function
M0005886cellular_componentplasma membrane
M0008150biological_processbiological_process
M0031514cellular_componentmotile cilium
M0036128cellular_componentCatSper complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000305
ChainResidueDetails
LALA676-ALA706
ISER62
IASP69
IASN60
IASP149
IASP153
IGLU160

site_idSWS_FT_FI2
Number of Residues63
DetailsTRANSMEM: Helical => ECO:0000269|PubMed:34225353
ChainResidueDetails
MMET17-HIS38
MARG52-SER72
MCYS85-LEU107

site_idSWS_FT_FI3
Number of Residues20
DetailsTOPO_DOM: Extracellular => ECO:0000269|PubMed:34225353
ChainResidueDetails
LGLN467-LEU565
LARG625-ASN652
LASN278-SER301
LHIS397-ALA410
MASN39-PHE51
MALA108-HIS116

site_idSWS_FT_FI4
Number of Residues20
DetailsTRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:34225353
ChainResidueDetails
HASN292
HASN502
HASN565
HASN749
HASN830
HASN888
HASN920
LGLU131-ALA151
HASN143

site_idSWS_FT_FI5
Number of Residues20
DetailsTRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:34225353
ChainResidueDetails
HASN915
EASN672
EASN915
EASN923
EASN1017
LTHR160-PRO180

site_idSWS_FT_FI6
Number of Residues22
DetailsTRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LILE219-ILE241

site_idSWS_FT_FI7
Number of Residues23
DetailsTRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LGLY254-GLN277

site_idSWS_FT_FI8
Number of Residues22
DetailsTRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LGLY302-PHE324

site_idSWS_FT_FI9
Number of Residues21
DetailsTRANSMEM: Helical; Name=7 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LLEU375-PRO396

site_idSWS_FT_FI10
Number of Residues21
DetailsTRANSMEM: Helical; Name=8 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LSER411-ILE432

site_idSWS_FT_FI11
Number of Residues20
DetailsTRANSMEM: Helical; Name=9 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LPHE446-CYS466

site_idSWS_FT_FI12
Number of Residues23
DetailsTRANSMEM: Helical; Name=10 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LLYS566-ILE589

site_idSWS_FT_FI13
Number of Residues19
DetailsTRANSMEM: Helical; Name=11 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LLEU605-PHE624

site_idSWS_FT_FI14
Number of Residues22
DetailsTRANSMEM: Helical; Name=12 => ECO:0000269|PubMed:34225353
ChainResidueDetails
LILE653-TYR675

site_idSWS_FT_FI15
Number of Residues1
DetailsSITE: Reactive bond => ECO:0000255|PROSITE-ProRule:PRU00798
ChainResidueDetails
LTHR499

site_idSWS_FT_FI16
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
LASN214
LASN486

site_idSWS_FT_FI17
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:34225353
ChainResidueDetails
LASN535

219869

PDB entries from 2024-05-15

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