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7EDP

Crystal structure of AF10-DOT1L complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Histone-lysine N-methyltransferase, H3 lysine-79 specificpolymer404715.51UniProt (Q8TEK3)Homo sapiens (Human)DOT1-like protein,Histone H3-K79 methyltransferase,H3-K79-HMTase,Lysine N-methyltransferase 4
2B
(A)
Protein AF-10polymer435007.91UniProt (Q5JT35)Homo sapiens (Human)
3C, D
(B, A)
waterwater18.034Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight9723.4
All*Total formula weight9723.4
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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