7E9K

Crystal Structure of POMGNT2 in complex with UDP and mono-mannosyl peptide (379Man long peptide)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, E	Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2	polymer	539	61563.9	4	UniProt (Q5NDF2) Pfam (PF04577) In PDB	Bos taurus (Bovine)	POMGnT2,Extracellular O-linked N-acetylglucosamine transferase-like,Glycosyltransferase-like domain-containing protein 2
2	C, F	mono-mannosyl peptide (379Man long peptide)	polymer	23	2317.7	2	UniProt (by SIFTS) (Q14118) In PDB	Homo sapiens
3	G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	A, B, D, E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	12	Chemie (NAG)
5	A, B, D, E	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	4	Chemie (UDP)
6	A, D	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
7	F, C	alpha-D-mannopyranose	non-polymer		180.2	2	Chemie (MAN)
8		water	water		18.0	908	Chemie (HOH)

Sequence modifications

A, B, D, E: 45 - 580 (UniProt: Q5NDF2)

PDB	External Database	Details
Gly 42	-	expression tag
Ala 43	-	expression tag
Pro 44	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	250891.1
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	20
	Total formula weight	4875.7
All*	Total formula weight	256191.2

*Water molecules are not included.