7E9K
Crystal Structure of POMGNT2 in complex with UDP and mono-mannosyl peptide (379Man long peptide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, E) | Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 | polymer | 539 | 61563.9 | 4 | UniProt (Q5NDF2) Pfam (PF04577) | Bos taurus (Bovine) | POMGnT2,Extracellular O-linked N-acetylglucosamine transferase-like,Glycosyltransferase-like domain-containing protein 2 |
| 2 | E, F (C, F) | mono-mannosyl peptide (379Man long peptide) | polymer | 23 | 2317.7 | 2 | UniProt (by SIFTS) (Q14118) | Homo sapiens | |
| 3 | G (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | H, I, J, M, N... (A, B, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 5 | K, Q, T, Y (A, B, D, E) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) | |||
| 6 | L, U (A, D) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 7 | AA, Z (F, C) | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
| 8 | BA, CA, DA, EA, FA... (A, B, D, E, C...) | water | water | 18.0 | 908 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 45 - 580 (UniProt: Q5NDF2)
| PDB | External Database | Details |
|---|---|---|
| Gly 42 | - | expression tag |
| Ala 43 | - | expression tag |
| Pro 44 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 250891.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4875.7 | |
| All* | Total formula weight | 256191.2 |
