7E8H
CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (J, L) | Dipeptidyl aminopeptidase-like protein 6 | polymer | 757 | 86277.7 | 2 | UniProt (P42658) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (Human) | DPPX,Dipeptidyl aminopeptidase-related protein,Dipeptidyl peptidase 6,Dipeptidyl peptidase IV-like protein,Dipeptidyl peptidase VI,DPP VI |
| 2 | B, H (I, K) | Dipeptidyl aminopeptidase-like protein 6 | polymer | 760 | 86490.9 | 2 | UniProt (P42658) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (Human) | DPPX,Dipeptidyl aminopeptidase-related protein,Dipeptidyl peptidase 6,Dipeptidyl peptidase IV-like protein,Dipeptidyl peptidase VI,DPP VI |
| 3 | C, I (F, H) | Kv channel-interacting protein 1 | polymer | 180 | 21145.8 | 2 | UniProt (Q9NZI2) Pfam (PF13833) Pfam (PF13499) | Homo sapiens (Human) | KChIP1,A-type potassium channel modulatory protein 1,Potassium channel-interacting protein 1,Vesicle APC-binding protein |
| 4 | D, F, J, L (B, A, D, C) | Potassium voltage-gated channel subfamily D member 2 | polymer | 494 | 55755.7 | 4 | UniProt (Q9NZV8) Pfam (PF11601) Pfam (PF02214) Pfam (PF00520) Pfam (PF07885) Pfam (PF11879) | Homo sapiens (Human) | Voltage-gated potassium channel subunit Kv4.2 |
| 5 | E, K (E, G) | Kv channel-interacting protein 1 | polymer | 181 | 21242.9 | 2 | UniProt (Q9NZI2) Pfam (PF13833) Pfam (PF13499) | Homo sapiens (Human) | KChIP1,A-type potassium channel modulatory protein 1,Potassium channel-interacting protein 1,Vesicle APC-binding protein |
Sequence modifications
J, L: 32 - 787 (UniProt: P42658)
I, K: 32 - 787 (UniProt: P42658)
B, A, D, C: 2 - 495 (UniProt: Q9NZV8)
| PDB | External Database | Details |
|---|---|---|
| Ala 31 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | - | expression tag |
| Ala 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Ala 31 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 450 | Asn 450 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 653337.6 | |
| All* | Total formula weight | 653337.6 |
