7E7C

Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein ENL	polymer	160	18872.7	1	UniProt (Q03111) Pfam (PF03366) In PDB	Homo sapiens (human)	YEATS domain-containing protein 1
2	B	Histone H3K27ac(24-27) peptide	polymer	4	487.6	1		Homo sapiens
3	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	A	IODIDE ION	non-polymer		126.9	2	Chemie (IOD)
5		water	water		18.0	53	Chemie (HOH)

Sequence modifications

A: 1 - 151 (UniProt: Q03111)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Asn 115	-	insertion
His 116	-	insertion
Leu 117	-	insertion
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	19360.3
Non-Polymers*	Number of molecules	4
	Total formula weight	377.9
All*	Total formula weight	19738.2

*Water molecules are not included.