7E74
Crystal structure of ENL YEATS domain T3 mutant in complex with histone H3 acetylation at K27
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein ENL | polymer | 155 | 18328.1 | 4 | UniProt (Q03111) Pfam (PF03366) | Homo sapiens (Human) | YEATS domain-containing protein 1 |
| 2 | E, F, G, H (E, F, G, H) | ALA-ALA-ARG-ALY | polymer | 4 | 487.6 | 4 | Homo sapiens | ||
| 3 | I, J, K (A, B, D) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 146 (UniProt: Q03111)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Lys 111 | Asn 111 | engineered mutation |
| - | Pro 112 | deletion |
| - | Pro 113 | deletion |
| His 147 | - | expression tag |
| His 148 | - | expression tag |
| His 149 | - | expression tag |
| His 150 | - | expression tag |
| His 151 | - | expression tag |
| His 152 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 75262.8 | |
| All* | Total formula weight | 75262.8 |
