7E74

Crystal structure of ENL YEATS domain T3 mutant in complex with histone H3 acetylation at K27

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Protein ENL	polymer	155	18328.1	4	UniProt (Q03111) Pfam (PF03366) In PDB	Homo sapiens (Human)	YEATS domain-containing protein 1
2	E, F, G, H	ALA-ALA-ARG-ALY	polymer	4	487.6	4		Homo sapiens
3		water	water		18.0	7	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 146 (UniProt: Q03111)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Lys 111	Asn 111	engineered mutation
-	Pro 112	deletion
-	Pro 113	deletion
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	75262.8
All*	Total formula weight	75262.8

*Water molecules are not included.