7E50
Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | AAEL006007-PA | polymer | 79 | 8820.9 | 1 | UniProt (Q1HRB8) Pfam (PF00050) UniProt (by SIFTS) (A0A1S4FCI9) | Aedes aegypti (Yellowfever mosquito) | Kazal domain-containing peptide |
| 2 | B (B) | Plasminogen | polymer | 255 | 27851.0 | 1 | UniProt (P00747) Pfam (PF00089) | Homo sapiens (Human) | MicroPlasminogen |
| 3 | C (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, E, F (B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A: 1 - 69 (UniProt: Q1HRB8)
B: 545 - 791 (UniProt: P00747)
| PDB | External Database | Details |
|---|---|---|
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 537 | - | expression tag |
| Gly 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Val 540 | - | expression tag |
| Pro 541 | - | expression tag |
| Arg 542 | - | expression tag |
| Gly 543 | - | expression tag |
| Ser 544 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36671.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 161.1 | |
| All* | Total formula weight | 36832.9 |
