7E3X

Crystal structure of SDR family NAD(P)-dependent oxidoreductase from exiguobacterium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Oxidoreductase	polymer	255	28159.9	2	UniProt (A0A177S9P4) Pfam (PF00106) In PDB	Exiguobacterium sp. KKBO11
2	A, B	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3		water	water		18.0	48	Chemie (HOH)

Sequence modifications

A, B: 2 - 249 (UniProt: A0A177S9P4)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Val 88	Phe 88	engineered mutation
Ile 127	Val 127	engineered mutation
Leu 138	Ala 138	engineered mutation
Met 142	Arg 142	engineered mutation
Val 190	Ala 190	engineered mutation
Ala 193	Ser 193	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56319.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1486.8
All*	Total formula weight	57806.5

*Water molecules are not included.