7E2W

Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with isocitrate and magnesium(II)

Replaces:  6IXU

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Isocitrate dehydrogenase (NAD(+)), mitochondrial	polymer	418	46823.7	4	UniProt (A0A096P8D3) Pfam (PF00180)	Ostreococcus tauri	OtIDH
2	E (A)	ISOCITRIC ACID	non-polymer		192.1	1	Chemie (ICT)
3	F (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	G (A)	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC)
5	H, J, M (A, C, D)	ISOPROPYL ALCOHOL	non-polymer		60.1	3	Chemie (IPA)
6	I, K, L (C, D)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
7	N, O, P, Q (A, B, C, D)	water	water		18.0	693	Chemie (HOH)

Sequence modifications

A, B, C, D: 20 - 429 (UniProt: A0A096P8D3)

PDB	External Database	Details
Gly 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	187295.0
Non-Polymers*	Number of molecules	9
	Total formula weight	862.1
All*	Total formula weight	188157.1

*Water molecules are not included.