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7DZM

Crystal Structure of the cross-restricted T18A TCR and HLAB8101 bound to HIV-1 Gag TL9 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
MHC class I antigenpolymer27832071.21UniProt (I3ZN85)
Pfam (PF00129)
Pfam (PF07654)
Homo sapiens (Human)MHC class I histocompatibility antigen,B-81 alpha chain,MHC class I protein
2B
(B)
Beta-2-microglobulinpolymer10011879.41UniProt (P61769)
Pfam (PF07654)
Homo sapiens (Human)
3C
(C)
Gag-Pol polyproteinpolymer91032.21UniProt (P03367)
UniProt (by SIFTS) (P04585)
Human immunodeficiency virus 1
4D
(D)
beta chain T18A TCRpolymer24127263.51Homo sapiens (Human)
5E
(E)
alpha chain T18A TCRpolymer20723008.71Homo sapiens (Human)
6F, G, H, I, J
(A, B, C, D, E)
waterwater18.0423Chemie (HOH)
Sequence modifications
A: 3 - 279 (UniProt: I3ZN85)
PDBExternal DatabaseDetails
Gly 2-expression tag
B: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight95254.9
All*Total formula weight95254.9
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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