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7DYG

Histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 2-(1H-pyrazol-3-yl)isonicotinic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lysine-specific demethylase 4Dpolymer33038093.21UniProt (Q6B0I6)
Pfam (PF02375)
Pfam (PF02373)
Homo sapiens (Human)JmjC domain-containing histone demethylation protein 3D,Jumonji domain-containing protein 2D,[histone H3]-trimethyl-L-lysine(9) demethylase 4D,Histone lysine demethylase 4D
2B
(A)
2-(1H-pyrazol-3-yl)pyridine-4-carboxylic acidnon-polymer189.21Chemie (0WS)
3C
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
4D
(A)
waterwater18.0327Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight38093.2
Non-Polymers*Number of molecules2
Total formula weight245.0
All*Total formula weight38338.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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